Large-scale Data Analysis Links Rare Diseases to Higher Covid-19 Mortality Risk

An England-Wide Study of Over 58 Million People has identified eight rare dissees that significantly Increased risks for covid-19-Relanted Mortality In Fullly Vaccinated Individuals. This Important Research Calls for Better Inclusion of Rare Diseases in Public Health Strategies, Including Future Pandemic Planning, Vaccão Polies, and NHS Service Provision.

The reset was published in The Lancet Digital Health.

HISTORICALLY, RARE DISEASES HAVE BEEN DIFFICULT TO STUDY AND NEGLED IN RESEARCH, IN PART DUE TO LACK OF LARGE-SCALE DATE. This means that peapople lives with rare conditions often struggle to get the treatment and support they have. AddiTeally, Rare Disease Patients Were Overloked in Public Health Planning-For Example, During the Covid-19 Lockdown Periods, The UK’s Shielding List Excluded Most Rare Diseases, Failing to Protect Highly Vulnerable Individuals.

Researchers at UCL (University College London) and the University of Glasgow Set Out to Harness The Power of Large-Scale Linked Data, to Uncover New Insights into Rare Diseases.

Using Linked Electronic Health Records (EHRS), They Investigated the Prevalence of Rare Diseases Across the Population, and the Risks That Covid-19 May Pose to People with these Conditions.

They Uncovered Eight Rare Diseases Linked with an Increeed Risk of Dying From Covid-19, and Found That People With Rare Diseases Were Nearly Five Times More Likely to Die From Covid-19 Than The General Population. The Conditions Carrying the Highest Risk Were Infertility Disorders and Kidney Diseases.

The Rarity of Some Diseases can contribute to a lack of comprehensive data due to lengthy waits for diagnosis. And the Study Period Spans Two ‘Waves’ of the Pandemic, It’s Difficult to Untangle The Effects of Different Covid-19 Variants, as wells Overlapping sympts in multiple illnesses.

However, This Study Takes Advantage of One of Our Health System’s Unique Strengths, Having Population-Wide Granular Data Coverage in ehrs and diversity in representation, HighLighting Significant Inequalities Faced by Specific Ethnic Groups In Which Some Rareases Were Disportiony n.

It’s also the first time an analytisi has Been Performed on so many rare dissees, and the impact of covid-19 on the people with such conditions, the landmark moment for rare disease research.

Living with a rare disease can be extremély challenging, from the diffult diagnosis to relevantless appointments to Manage Health and Well-Being. But these Findings Fill A Critical Knowledge Gap, Emphasizing the Power of Electronic Health Record Data to Bring to Light The Prevalence and Outcomes of Rare Diseases.

Co-Author Professor Honghan Wu, University of Glasgow and Formerly UCL, Said, “Early Detection Means Earlier Intervention and Better Treatment and Support. The net.

“So Research Harnessing NHS Date for impact through Linking Ehrs Has Enors Potential to Inform Care and Public Health DECISION-MAKING, Beyond the Covid-19 Pandemic, Special for Patient Population That Are Far Too Often Neglected.”

Provided by Health Data Research UK