The Following is a summary of “Hydrophobic and Hydrophilic Iols in Patients with Uveitis – The Randomized Clinical Trial,” Published in the February 2025 Issue of Ophthalmology by Pålsson et al.
Researchers conducted the retrospective study to compare the infmmatory response, visual accurate, and complications of 2 intraocular lenses (ols) in patients with and Whithout uveitis.
They Randomized Patients with and Without Uveitis, ELIGIBLE FOR CATARACT SURGERY, TO VEEATE EITHER TO HYDROPHOBIC OR HYDROPHILIC SQUARE-EDGED IOL. In Cases of Bilateral Surgery, 1 Eye Received A Hydrophobic Iol and the other a Hydrophilic IOL. The Outcome Measures Included Visual Accuity, Flare, and Central Foveal Thickness.
The Results Showed 34 (61%) Patients with Uveitis (52 Eyes) and 22 (39%) Patients with Non-Uveitis (38 Eyes) and No Significant Difference in Corrected Visual Distance (CDVA) Was Observed Between The 2 Iol Materials. Flare Measurements at 6 Months Post-surgery Showed No Significant Difference Between Eyes Receueving Hydrophilic or Hydrophobic Iols; Mean Differences Were – 3.2 (SD ± 20.7) PH/MS In Uveitis Eyes (P = 0.53) and-0.6 (sd ± 7.5) pH/ms in non-uveitis eyes (P = 0.77). In Significant Difference in Cystoid Macular Edema (CME) was Found in Patients with Uveitic Receiving Hydrophobic (n = 2; 8.0%) vs Hydrophilic Iols (n = 6; 22.2%; P = 0.25).
Investigators concluded that neither Hydrophobic Nor Hydrophilic Iols Demonstrated Superiority Regarding Postoperative Inflammation or CME Rates in Patients with Uveitic Undergoing Cataract Surgery, Thought Both Types of Iols Iols Ilols CDVA.
