
An in vivo imaging setup at issta. Reflections of co-first authors tomas Vega-Zuniga and Olga Symonova in the Mirror of the Virtual Reality Setup That is part of a Two-Photon Microscope. This System Allows in Vivo Imaging of the Brains of Awake and Behaving Mice. Credit: Ista
WHY MENTAL OUR IMAGES STAY SHARP EVEN WHEN WE ARE MOVING FAST? Team of Neuroscientists LED by Professor Maximilian Jösch at the Institute of Science and Technology Austria (ITA) has identified a mechanism that corrects visual Distortions caused by movement in animals. The Study, Driven in Mice, identifies a core function that can be generalized across the vertebrate visual system, including primates such as human. The Findings Are published in Nature Neuroscience.
Rapid its rapid defelopment in recent decades, the video camera industry is still catching up with the capabilities of the human eye. In Private, Action Cams Are Designed to Capture Footage While Immeed in the Action. The We Judge Footage Quality and the Need for Fancy Equipment and Optimization Software Based on the Abilities of the Human Eye, Questions: How of It Eyes Do It So Well?
Researchers LED by Professor Maximilian Jösch at the Institute of Science and Technology Austria (ITA) have now answed This question with the force technical tour. The Three Scientists and Co-First Authors Tomas Vega-Zuniga, Anton Sumser, and Olga Symonova Combined a Range of State-Of-The-The-Art Techniques to Identify a Brain Region in the Mouse That Can Predict and Minimize How Movements Distort The Visual Signal . This Brain Region, Residing Deep In The Brain, Lurally Copies The Brain’s Motor Commands to Suppress Movement-Anduced Distortions.
“We show that the image correction happons very early during visual processing – Before the information is transmitted to other areas of the brain that are known to representation more complex visual features,” says jösch. “Thus, we demonstrate that the mammalian brain devenes strates to compensate for movement efficiently by predicting its effects on vision.”

Scientists Olga Symonova and Tomas Vega-Zuniga at the in vivo Imaging Setup at the Institute of Science and Technology Austria (Ista). Credit: Ista
Formula 1 Footage Without Postproduction
The Scientists Pinpointed the “VlGN-Geniculate Lateral Ventral” The Brain Region Responsible for This Built-in High-Tech Video Optimization Software. It is located in the side Thalamus, an Egg-Shaped Structure in the Center of the Brain, Below the Cerebral Cortex.
The Researchers Found that the vLGG integrates various engine and sensory signs from through the brain, and acts a hub to compute a compute the comprehensive corrective signal. One Example is the ‘unblurring’ of visual signals as soon as the eye moves. This AllWs Later Stages of Visual Processing to Be Computed Much more efficiently.
“Think About Strategies To Get Good Video Footage During A Formula 1 Race. BECAUSE The Cars Are Moving So Fast, The Exposure Time has to Be Reduced To Make The Final Footage Less Blurry,” Explains Jösch.
Such Footage Can Be Broadcast Live on Television Without Any Post-Production. This is Roughly What the vlgg does to help us distinguish our owns motion from that of the world around us. However, Unlike a Stationary Camera Showing The Cars Racing By, The Brain’s Vlgn Signals Similarly to the Formula 1 “Driver’s Eye” Onboard Footage, Dynamically Compensating for the Motion To Stabilize What We Perceive.

Scientists Tomas Vega-Zuniga and Olga Symonova and Professor Maximilian Jösch at the Institute of Science and Technology Austria (ITA). Credit: Ista
A Core Function That Flew Under The Radar
PREVIOUS WORK HAS SEARCHED FOR A MEHALISM THAT Effectively Adjusts Vision During Motion. Much of This Work has focus on Studying Saccadic Eye Movements in Primates. Saccades are rapid shifts of the center of gauze from one part of the visual field to another, the movement that should theoretically blur or cream to mental image -but does not always of the OS. However, These Studies Focused on Cortical Structures That Are Involved in Much Later Stages of the Visual Processing Pathway.
Opposed to this, our sensory System is constantly “bombarded” by Various Types of Movements. So, The Earlier the Brain Can Compensate for Movement in Vision, The Better, Explains Jösch. “Our Findings Were Likely Not Observed Until Now Because We Had Been Looking at Stages in the Visual Processing Pathway Where the Image Had Already Been Corrected.”
Now, the Ista Scientists Hypothesize That Their Findings on the Vlgn in Mice Representation A Core Function in the Mammalian Brain. “Similar structures exist in primates, and this is very likely the case for human, too. This makes our results see exciting,” says jösch.
The virtual reality System to image the brain in vivo
Among the cutting-edge technologies the Ista scientists used was a custom built two-photon calcium imaging microscope. This technique allows the team to measure vlgg neuronal activity in the intact brain while the mice are awake and are behaving normally in a virtual reality system.
“With this setup, we can look into the brain of a mouse and observe the activity of the vlgg nerves while the mice are wandering through the virtual world,” Says Jösch.
Using This Method, The Team Discoved That the VLGN Receives Very Specific Copies of Behavioral Instructions That Can Be Used To “Unblur” Visual During Movement. “This Paper Was A Real Technical Tour of Force, Using Multiple Approaches to Gain A Comparthensive Understanding of the Role of the Vlgn in the Mouse Brain,” Says Jösch. “We are excited to See where the follow-up Studies Will Take us.”
More information:
Thalamic Hub-And-Spoke Network Enables Visual Perception During Action by Coordinating Visuomotor Dynamics, Nature Neuroscience (2025). DOI: 10.1038/S41593-025-01874-W
Citation: High-Tech Video Optimization in Our Brain: How the Brain Unblurs Vision During Movement (2025, February 10) Retrieved 10 February 2025 from
This document is Subject to Copyright. Apart from Any Fair Dealing for the Purpose of Private Study or Research at Part May Be Reproduced Without The Written Permission. The Content is Provided for Information Purposes Only.