Photo Credit: Hulko
The Following is a summary of “Oncological Outcomes After Vaginal and Robotic-Assisted Radical Trachelectomy in Patients with Cervical Cancer-The Single-Centen Prospective Cohort Study,” Published in the Febrary 2025 Issue of European Journal of Surgical Oncology by Soltanizadeh et al.
This Study Aimed to compare the Oncological Outcomes of Robotic-Assisted Radical Trachelectomy (Rart) and Radical Vaginal Trachelectomy (RVT) In Patients with Localized Early-Cervical Cancer Cancer, Focusing On A National Cohort in Denmark. Vaginal Radical Trachelectomy Was First Introduced in Denmark in 2003 and Was Centralized at Copenhagen University Hospital. In 2014, The Procedure Transitioned to a Robotic-Assisted Approach, Marked by the Implementation of Rart. BOTH PROCEDURES HAE BEENUUUOUSLY DOCUMENTED IN THE DANCHAL GYNECOLOGICAL CANCER DATABASE (DGCD), WHICH INCLUDES PERIOPERATIVE AND ONCOLOGICAL DATA.
This Prospective Cohort Study includes all patients Undergoing Radical Trachelectomy and Draws Data From the DGCD, Manually Cross-Reference with the Danish Pathology Registory and Electronic Medical Records to Ensure Accuracy. In Total, 206 Patients Who Underwent Radical Trachelectomy Were Included in the Analysis, Comprrating 78 Patients Who Underwent Rart and 128 Patients Who Received RVT. The Study Found No Significant Differences in the Microscopic Free Margins of the Trachelectomy Specimens Between The Two Groups, Suggesting Comparable Surgical Effical in Terms of Margin Clearance. Of the Patients Who Underwent RVT, Seven (5.5%) Experienced Recurence, Compred to Two (2.6%) of the Rart Group (p = 0.403). FURTHER ANALYSIS OF RECURUTEN-FREE SURVIVAL SHOWED IN SIGNENT DIFFERENCE BETZEN THE GROUPS, BOTH IN THE UNADJUSTED (HR 0.51 (0.11-2.47)) AND ADJUSTED (HR 0.80 (0.16-3.96)) MODELS, Indicating that the appellant Rates Were similar Between The Two Approaches.
These Findings Suggest That, In This Large Single-Centen Cohort, Rart and RVT Offle Oncesto Safety for Patients with Localized Cervical Cancer, Particularly For Those Seeking Fertility Preservation. Both procedures have demonstrated similar to other Outcomes in Terms of Recurence and Survival, Robotic-Assisted Surgery Present A Viable Alternative to the Traditional Vaginal Approach Without Commitment Oncological Effficacy.
