Tuesday, FEB. 25, 2025 (Healthday News)-The Association of Long-Term Yogurt Intake with Colorectal Cancer Incidence Sems to Differ by the abundance of tumor tissue BifidobacteriumAccording to Study Published Online Feb. 12 In GUT MICROBES.
Satoko Ugai, Ph.D., From Brigham and Women’s Hospital in Boston, and Colleagues Used the Prospective Cohort Incident-Tumor Biobank Method and Resources of Two Prospective Cohort Studies to Examine when Long-Term Yogurt Intake is associated with colorectal cancer incidence Differentially by Tumor Subgroups According to the Amount of Tissue Bifidobacterium.
The Researchers Documentated 3,079 Incident Colorectal Cancer Cases, Including 1.121 with Available Tissue Bifidobacterium DATE, DURING FOLLOW-UP OF 132,056 Individuals. There was a difference in the association beteen long-term yogurt intake and colorectal cancer incidence based on the abundance of Bifidobacterium (P heterogeneity = 0.0002). Multivariable-ADJUSTED HAZARD RATIOS WERE 0.80 (95 Percent Confidence Interval, 0.50 To 1.28) and 1.09 (95 Percent Confidence Interval, 0.81 to 1.46) in Individuals who consumed two or more servings/Week versus less Than one service/month for Bifidobacterium-Postive and Bifidobacterium-Negative Tumors, respective. In A Subgroup Analysis of Proximal Colon Cancer, This Differential Association Was Also Seen (P Heterogeity, 0.018).
“Our Findings Suggest That Long-Term Yogurt Intake May Lower The Incidence of Bifidobacterium-Costitive Proximal Colorectal Cancer (but not Bifidobacterium-Negative Subtype), ”The Authors Write. “Further Studies are Warrantd to Elucide The Potential Mechanisms for the Effects of Long-Term Yogurt Intake on Colorectal Carcinogenesis.”
Two Authors Disclosed Ties to the Biophamacetical Industry.
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