Socioeconomic Factors Fuel Global Inequalities in Alzheimer’s Disease Burden, Analysis Finds

An Analysis of the Global Burden and Temporal Trends of Alzheimer’s Disease and Oter Dementias (Adods) Reveals Significant Cross-country inequalities Associated with a Series of Sociodemographic Development-Relanted Risk Factors, Such As Education, Incom, Fertility, and Health Expected.

The New Study in the American Journal of Preventive Medicine Calls for the Development of Targeted Prevention and Control Strategies in Different Countries.

The Burden of Adods has Risen Globally Over the Past Three Decades. The Authors of This First Systematic and Comprehensive Global Study Analyzing Date FROM 1990 to 2021, Including Data from the Global Burden of Disease 2021 Study and the World Bank, Found That There Are Significant Fixes in Numbers, Rates, and Age-StandarDized Rates of Disability-Adjusture Life Years Across 204 Countries and Territories.

Lead Investigator Ya Fang, MD, Ph.D., School of Public Health, Xiamen University, China, SAYS, “Adods Currently Pose to Major Global Public Health Challenge. They Stand As a Leading Cause of Functional Loss and Dependence Among Older Individuals Worldwide. There are in the definitive Treatments Capable of Fully Resolving Adods.

“Furthermore, Research Exploring the Relationship Between Sociodemographic Development-Relanted Factors and Health Inequalities Associated with Adods is currently Limited. Therefore, We Aimed to Establish This Connection by Assessing the Socodemographic Development Development Indicators Such As Education, Incomes, Fertility, and Health Experiture on Adods’ Health Metrics. “

The Study Found That Approximately Two-Thirds of Individuals with Adods Workwide Now Low-and Low-Middle Incomed Countries, and As Population Grow, The Number Of Cases with Adods In These Countries is Expected in High-Icon Counties. Therefore, The Disease Burden of Adods is Believed to Be Greater in Low-and Middle-Ancome Countries, Where Individuals Are More Likely to Face Poverty and Limited Access to Health Care.

However, Even in Countries with High Sociodemography Development Levels, Such As Luxembourg, Switzerland, and the United States, Prophend Relative Compartable Health Care Systems, The Disease Burden of Adods Remains High Because of the Specific Distribution of Adod Risk Factors in These Countries, Such As Obesity, Poor Diet, and Diabetes.

Another Noteworthy Finding is that fumales exhibited a Notably Higher Burden of Adods Than Act Age Groups, Corroborating Previous Research That Identifies Female Sex A Risk Factor for Accelerated Cognitive Decline. Gender Differences in Disease May Be Influenced by Reproductive Capacity, Sex Hormones, Genetic Predisposition, and Epigenetics.

Females are special sensitive to hormonal fluctations, particularly premenstrual, perinatal, and menopausal periods. Estradiol and Progesterone Flutations During Pregnancy Impact Maternal Brain Structure and Function, Such That the Reproductive History of Women May Affect Brain Aging and Disease Risk.

Dr. Fang Concludes, “This Study Integrated the Global Burden of Disease 2021 and World Bank Data, and, to the Authors’ Knowledge, is the First Systematic and Comprahensive Study on Cross-Cross-Cross-Inquality Associated with Sociodemographic Development-Relanted Factors.

“Other Significant Strengths of This Study Are It Long Observation Period, Wide Geographical Range, and Extensive Coverag. Based on the Results, It is necessary to Further Control Risk Factors of Adods by Promoting A Healthy Diet and Regular Exercise for Preventing The Development of Adods Infed Countries.

“However, Enhancing Basic Health Care, Improving Medical Resource Access and Affordability, and Raising Adod Awareness Among the Public In Development Countries Are Also Vital.”