Sex differences in psoriasis impact perceptions of dissease, treatment, & quality of life

Health & Medicine


Photo Credit: Oatawa

Data from the Swiss psariasis Registry and the EurogoGuiderm Guidelines Highlight Sex Differences In Psoriasis and the Impact on Health-Relanted Quality of Life.


AT MAUI DERM 2025, Multiple Sessions Focused on the Management of Psoriasis. In A Panel Discussion with Joel Gellfand, MD, and April W. Armstrong, MD, MPH, The Clinicians Discussed The Development of “Patiented Treatment Plans to Maximize Outcomes and Improve Quality of Life (QOL),” According to Dr. Gelfand.

In His Introduction, Dr. GELFAND NOTED the Halthcare Halthcare Forms in Psoriasis. While Drs. GELFAND AND ARMSTRONG SPECIFICALLY ADDRESSED RACIAL AND ETHNIC FIELDS IN PSORIASIS DURING THEIR PRESENTATION, THE CHRONIC INFEMMATORY SKIN CONDITION RESULTS IN UNique Management Challenges DUE TO SEX-REFLESS FIXES.

In A Separate Study That Was Not Gifted at the Meeting, Julia-Tatjana Maul, MDand Colleagues Examined Real-World Data from the Swiss Psoriasis Registry (SDNTT). The Findings Highlight How Men and Women Experience Psoriasis Differently, Impacting Their Health-Relanted Quality of Life (HRQOL).

Clinical Guidelines & Barriers to Treatment

Sex-Based Arunches In Psoriasis Go Beyond Biological Different. Women Report A Higher Psychological Burden, Social Stigmatization, and Reduced Qol Compred With Men, Propitle often Present with Lower Objective Disease Severity Scores. Dr. Maul and Colleagues Found That Women Had Significantly Higher Baseline Dermatology Life Quality Index (DLQI) Scores Than Men, Indicating Greater Perceived Disease Impact. This disparity Persisted over 2 Years, Particularly Among Women Treated with iL-12/23 Inhibitors.

These Findings, Which Were Published in Dermato-venereological actalign with Previous Research Suggesting That Women Experience Greater Mental Health Challenges and Lower Satisfaction with psoriasis Treatments. The Psychological Toll of Psoriasis, Particularly in Women, Can Affect Adherence to Therapy and Overall Treatment Success, Further Complicating Disease Management.

Current guidelines for systemic psoriasis treatment, such as the Euroguiderm guidelinesEmphasize Disease Severity and Response To Therapy But Lack Specific Recommendations Addressing Sex-Based Different.

The Findings from Dr. Maul and Colleagues Support the Need For A More Personalized Approach That Accounts for Hrqol, Treatment Expectations, and Patient-Reported Outcomes.

The EUROGUIDERM GUIDELINE On Systemic psariasis treatment notes that a significant barrier to equitable psoriasis management is the historical under-representation of women in clinical trials. ADDITIONALLY, DERMATOLOGISTS MAY UNDERESTIMATETE THE PSYCHOLOGICAL IMPACT OF PSORIASIS IN WOMEN. Addressing these Barroiers Requires Increased Use of Patient-Reported Outcome Measures (Proms) In Clinical Decision-Making, Enhanced Clinician Awareness of Sex Different In Psoriasis Burden, and More Clinical Trials That Stratify Treatment Responses by Sex. Clinicians Should Also Be Mindful of UNCONSCIOUS BIASES THAT May influence Treatment Decisions and Work Toward Fostering A More Patientored Approach In Psoriasis Care, The Authors of the Guidelines Noted.

Treatment, Communication & Management Strategies

Personalized Treatment Strategies Should Consider Both Clinical Severity and Hrqol Measures, The Guideline Authors Continue. Women May Benefit from Early Intervention with Biologic Therapies That Effectively Address Both Physical and Psychological Disease Burden. Regular HRQOL Assessments Should Be Integrated into Treatment Planning to Ensure Therapies Align with Patient Needs. IL-12/23 Inhibitors May Require Closer Monitoring in Female Patients, Given Their Association With Persistently Lower Qol Scores in the Study Cohort. Physicians Should Address Psychosocial Factors, Such As Depression and Self-Estem Issues, Which Disprortionity Affect Women with psoriasis. Expanding Access to Mental Health Support Services and Encouraging A Multidisciplinary Approach To Psoriasis Care Can Improve Patient Outcomes and Long-Term Well-Being.

TOGETHER, these Research Findings Emphasize the impact of sex arrangements in perceptions of disease, Treatment Satisfaction, and Long-Term Qol. FURTHER, The Swiss Psoriasis Registry Study Reinforces The Need For Gender-Sensitive Approach to Psoriasis Management.

By Incorporating Hrqol Assessments, Tailoring Treatment Choices, and Improving Patient Education, Physicians can be bridge the gap in psoriasis care and teach Better Outcomes for All Patients. The Research Continues to Explore the Intersection of Gender and Disease Burden, Healthcare Professionals Must Remain Adaptable in Their Approach, Striving for Equitable Care That Addresses Both the Physical and Emotional Aspects of Psoriasis.



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