Oral Contraceptives and Smoking Shown to Impact Steroid Hormone Levels in Health Adults

Steroid Hormone Levels in Healthy Adults Are Influenced by Oral Contraceptives and Smoking, as the other lifestyle Choices and Factors Such As Biological Sex and Age, According to New Research That Just Been published In the Journal Science Advances.

The Objective of the Research Was to Expand Knowledge and Understanding of Steroid Hormone Levels, Including Corticoids and Sex Hormones, In Healthy Women and Men Over a Broad Age Range. This is the first study to Analyze Such a Large Number of Hormones in Nearly 1,000 Healthy People, Filling A Major Gap in the Knowledge of Molecules That Are Important For Out Day-to-Day Well-Being.

The Work was conducted by Members of the Milieu Interrieur Consortium and Led by Dr. Darragh Duffy (Institut Pasteur) and Dr. Molly Ingersoll (Institut Pasteur and Institut Cochin (Inserm U1016, CNRS, Université Paris Cité). Dr. Jamie Sugrue, the Trinity College Dublin Graduate, Now Postdoctoral Researcher at the Institut Pasteur, is the co-first autho. Interieur Consortium Teams.

The Team Involved in This Current Study Found That Hormone Levels Vary According to An Individual’s Age and Sex, But that are also associated with many other factors, Such As Genetics and Common Behaviors.

Notably, Many Steroid Hormone Levels, Beyond Sex Hormones, Are Influenced by Oral Contraceptive Use in Women, While In Men, Smoking Was Associated with Altered Levels of Nearly Every Steroid Hormone Measred.

Addihthanly, Measurement of Hormones in the Same Owners 10 Years After the Original Visit Showed That Decrases In Specific Androges Were Associated with Diverse Diverse Diveases in Aging Men, Implying Thatse Hormones – Which Are Associated with Physical Characteristics, and Supporting Strong Bones and Red Blood Cell Production – Play A Role in Disease Development.

This finding – Aamong Others – Gives The Team Numerous Avenues to Pursue in Future Research.

Dr. Sugrue Said, “Even in Healthy People, Imamune Responses Can Vary Dramatics. A First Step Towards Understanding How Hormones Impact Immunity, We Worked To Underselves Themselves Vary People. Our Study Provides A Significant Resource for The Research Community, and Generats Many New Hypotheses for Further Research. Our Next Steps Will Focus on Underssection How Variation in Hormone Levels Contribute to Differences in the Immune Response Between People. “

“My current project is specifically focused on variation in antiviral imamune responses in healthy peaple, and in many ways is a continuation of work that i Started during my ph.d. with Prof. cliono o’farelly at trinity, where we work antiviral immeli system variation variation variation variation variation variation Resistance to hepatitis c virus infection. By incorporating the hormone measures into my current analyzis i hope to uncover exciting new insights. “

Cliona O’Farrelly, Professor of Comparative Immunology in Trinity’s School of Bochemistry and Immunology, Aded, “IF the Covid Pandemic Taught Us Anything It Was How Different All IMMEMBER SYSTEMS Are, and Being Part of the Milieu Interrieur Collardation is Giving US Trinity Researchers A Wonderful Opportunity to Study The Molecular and Genetic Mechanisms Responsible for these Differences at Scale. “

CO-FIRST AUTHOR, Dr. Léa G Deltourbe, Institut Pasteur & Institut Cochin, Added, “This Study Brings Much Needed Date to A Subject That Receiving In The Mainstream News and On Social Media Platforms, Providing the Strong Basis for Investigating The Role of Steroid Hormones In Health and Disease, Including the Impact of Endocrine Disruptors, The Link Between Stress and Cortisol, and the Role of Sex Hormones on Our Well-Being. “

One examines, Understanding the Potential Effects of the Contraceptive Pill on Physical and Mental Health Should Lead to a Better Quality of Life for Women Choosing to Use This Form of Medication.