
Dot Plots Showing The Association of PD AAO With a) Statin Intake, b) NSAID Intake, c) Adrenergic Blockers Intake, and d) Smking History, Which Were the Four Strongest Independent Predictors of Aao in the Multiple Regression Analysis. CREDIT: Journal of Neurology (2025). DOI: 10,1007/S00415-025-12989-2
In a New Cedars-Sinai Study of Parkinson’s Disease Patients, thhose who have Taken Common Medications to Control Pain, Blood Pressure, Diabetes or Cholesterol Saw Their Symptoms Begin Years Later Than Patients Who Never Took These Medications. The Investigators, Whate Work Was published In the Journal of NeurologySAY LARGER STUDIES ARE NEEDED TO DETERMINE WHETHER THE DRUGS IN FACT DELAYED THE OSET OF PARKINSON’S.
The Analysis of Data On 1.201 Cedars-Sinai Patients with Parkinson’s Disease Found:
- Patients Who Tok Nonnsteroidal Anti-InflamMatory Drugs, Including Ibuprofen and Aspirin, Were on Averag 8.6 Years Older at the Onset of Symptles Than Patients Who Had Not Taken The Medications.
- Patients Who Took Statins To Lower Cholesterol Were an averag of 9.3 Years Older at Symptom onSet.
- Those Taking Beta Blockers to Reduce Blood Pressure Averaged Being 9.6 Years Older When they have Symptoms First Appeared When Compred with Pats Not Exhibited to These Medications.
Parkinson’s Disease, the degenerative Brain Condition, is associated with tremors, balance problems and slowed movement; AN INDIVIDUAL’S RISK OF DEVELOPING IT INCREASES WITH AGE. ITS CAUSE IS UNKNOWN, THOUGH GENETICS PLAY A ROLE IN SOME CASES.
“The Medications We Studied Have Common Features That May Explain Their Effect on Parkinson’s Disease, Including The Ablicity to Control Infummation,” Said Michele Tagliati, MD, Vice Chair of the Neurology and Director of the Division of Movement Disorders at Cedars-Sinai and Senior Author of the Study.
“While AddiTeies Are Needed to Monitor Patients Over Time, This Research Suggerses That the Medications Studied Also Help Control the Cellular Stress Response and Brain Infummation, Which May have a Prominent Role In Delaying The Development of Parkinson’s Disease.”
More information:
Camille Malat et al, Adrenergic Blockers, Statins, and Non-Steroidal Anti-Inflammory Drugs Are Associated with Later Age at Onset in Parkinson’s Disease, Journal of Neurology (2025). DOI: 10,1007/S00415-025-12989-2
Citation: Common Medications May Delay Parkinson’s Onset (2025, April 14) Retrieved 14 April 2025 from
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