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The Following is a summary of “Revolution ex vivo skin imaging: 3D Charachterization of Skin Tumors with Ex vivo LC-CT. A Pilot Study,” Published in the April 2025 Issue of Dermatology by Rosés-Gibert et al.
Various Imaging Techniques, Including Reflectance Confocal Microscopy (RCM), Optical Cohernce Tomography (OCT), and Line-Field Confocal Oct (LC-CT), Were Available for Skin Evaluation; However, Need Persisted for Enhanced Imaging Methods to Improve Understanding of Tumor Histology and Surgical Margin Detection.
Researchers Drive the Retrospective Study to Evaluate the Quality of Ex Lc-Cet Images in Cutaneous Tumors, Characterize Their Morphological Features, and Compare the Findings With Demoscopy, In Vivo RCM, and Histology.
They Enrolled Individuals AGED 18 Years and Older with Cutaneous Tumors on the Trunk or Limbs Between June 2022 and July 2023. Data from 10 Tumors – Seborrheic Keratos, Basal Cell Carcinomas, and Melanocytic Nevi – Were Collected, Including Clinical, Clinical, DEMOSCOPIC, RCM, EX LIV LC-CET, and HISTOPATHOLOGICAL IMAGES.
The Results Showed that ex vivo lc-oct Generated High-Quality Images Comparable to Those from in vivo Systems, OffeRing Three-Dimensional Views of Excised Tumors. The Imaging Achieved Cellular-Level Resolution and Demonstrated Strong Alignment with RCM and Histopathological Findings.
Investigators Concluded that ex vivo LC-CET SHOWED POTENTIAL FOR ENHANCING THE ASSESSMENT OF SKIN TUMORS AND COULD IMPROVE DERMATO-NECOLOLOGICAL SURGERY, SPECIALLY REGARDING MARGIN CONTROL.
