Fatty muscles increase the risk of serious heart disease regardless of overall body weight, study shows

Researchers used CT scans to analyze each patient’s body composition, measuring the amounts and location of fat and muscle in a section of their torso. SAT = subcutaneous adipose tissue SM = skeletal muscle IMAT = intermuscular adipose tissue. Credit: Vivianty Taqueti / European Heart Journal People with pockets of fat hidden inside their muscles […]

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Exercise-Induced Worsening of Atrial Functional Mitral Regurgitation in HFpEF

Photo Credit: ttsz The following is a summary of “Impact of Exercise on Atrial Functional Mitral Regurgitation and its Determinants: An Exercise Echocardiographic Study,” published in the January 2025 issue of Cardiology by Schutter et al. Atrial functional mitral regurgitation (AFMR), a distinct type of mitral regurgitation observed in patients with atrial fibrillation and heart […]

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Keeping blood pressure under control is critical. There’s a new option for tough cases

In this photo provided by Massachusetts General Hospital, patient Mike Garrity, center, speaks with Drs. Joe Garasic, left, and Randy Zusman in Boston, on Sept. 25, 2024. Credit: Jeffrey Andree/Massachusetts General Hospital via AP Nothing doctors prescribed controlled Michael Garrity’s dangerously high blood pressure—until they zapped away some nerves on his kidneys. If that sounds […]

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Recording BMI in Primary Care for Managing Obesity in the Netherlands

Photo Credit: designer491 The following is a summary of “Recording practices of body mass index, overweight and obesity by Dutch general practitioners: an observational study,” published in the January 2025 issue of Primary Care by Hout et al. Routine body mass index (BMI) recording in electronic health records (EHR) can assist general practitioners (GPs) in […]

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Obesity won’t be solely defined by BMI under new plan for diagnosis by global experts

A man uses measuring tape on his waist in California on Jan. 9, 2025. Credit: AP Photo/JoNel Aleccia A group of global experts is proposing a new way to define and diagnose obesity, reducing the emphasis on the controversial body mass index and hoping to better identify people who need treatment for the disease caused […]

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Impact of Serum Indoxyl Sulfate on PD Outcomes

Photo Credit: 7activestudio The following is a summary of “Association between serum total indoxyl sulfate, intraperitoneal inflammation, and peritoneal dialysis technique failure: a 3-year prospective cohort study,” published in the December 2024 issue of Nephrology by Stepanova et al. The role of protein-bound uremic toxins, particularly indoxyl sulfate (IS), in peritoneal dialysis (PD) complications is […]

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Mental struggles become the deadliest construction industry danger

Credit: Unsplash/CC0 Public Domain Frank Wampol had a dark realization when he came across some alarming data a few years ago: More than 5,000 male construction workers die from suicide annually—five times the number who die from work-related injuries, according to several studies. That’s considerably more than the suicide rate for men in the general […]

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Charlson Comorbidity Index Can Discern Post-Kidney Transplant Risks

Photo Credit: Marco Marca Patients with a preop, age-adjusted Charlson Comorbidity Index score higher than 3 had a much greater risk for postop complications after kidney transplant. Patients with a preoperative, age-adjusted Charlson Comorbidity Index (ACCI) score greater than 3 had a significantly elevated risk of postoperative complications following kidney transplantation compared with other renal […]

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HIV vaccines can lead to antibodies against antibodies

Scripps Research scientists found that HIV vaccination can lead to the production of anti-immune complex antibodies (blue) that recognize immune complexes composed of antibodies (green) rather than the HIV virus alone (gray). Credit: Scripps Research Many vaccines work by introducing a protein to the body that resembles part of a virus. Ideally, the immune system […]

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Transfusion Medicine in 2025: Challenges, Innovations, & the Clinicians’ Role in Driving Blood Donation

Photo Credit: Champpixs ADRP Advisory Board Member Amanda Hess discusses advances in transfusion medicine, challenges blood centers face, and how clinicians can boost blood donation. The need for blood donations in the US remains significant. According to the Association for Blood Donor Professionals (ADRP), over 15 million units of red blood cells, platelets, and plasma […]

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